Description

TB-500 Fragment

Ac-LKKTETQ | Thymosin Beta-4 17–23 Fragment | Peptide Research Compound

TB-500 Fragment is a synthetic, N-terminally acetylated heptapeptide corresponding to residues 17–23 of thymosin beta-4 (Tβ4). Its commonly documented sequence is Ac-LKKTETQ, consisting of seven amino acids with N-terminal acetylation. PubChem lists the compound with molecular formula C₃₈H₆₈N₁₀O₁₄ and molecular weight of approximately 889.0 g/mol.

The fragment is relevant to laboratory research involving peptide chemistry, sequence characterization, analytical chemistry, molecular interactions, and comparative peptide studies.

TB-500 Fragment Research Profile

TB-500 Fragment is a short peptide derived from the sequence of full-length thymosin beta-4. The fragment is distinct from the complete 43-amino-acid thymosin beta-4 molecule and should not be described as chemically identical to the parent peptide.

The exact peptide sequence and terminal modifications are important for accurate identification and reproducible laboratory research.

TB-500 Fragment Chemical Information

Specification Details
Product Name TB-500 Fragment
Alternative Description Thymosin Beta-4 17–23 Fragment
Sequence Ac-LKKTETQ
Sequence Length 7 amino acids
Molecular Formula C₃₈H₆₈N₁₀O₁₄
Molecular Weight Approximately 889.0 g/mol
CAS 885340-08-9
Compound Type Synthetic peptide fragment
Parent Peptide Thymosin Beta-4

PubChem records TB-500 with the sequence LKKTETQ and N-terminal acetylation, represented as [acetyl]-LKKTETQ-OH.

TB-500 Fragment Research Applications

TB-500 Fragment may be investigated in controlled laboratory research involving:

  • Peptide chemistry
  • Peptide sequence characterization
  • Molecular characterization
  • Analytical identification
  • Purity and assay testing
  • Peptide stability studies
  • Structure–activity research
  • Comparative peptide analysis
  • Formulation research
  • Analytical method development

Key Characteristics

Defined Seven-Amino-Acid Fragment

TB-500 Fragment is a defined heptapeptide with the sequence Ac-LKKTETQ, allowing researchers to characterize the material using appropriate analytical methods.

N-Terminal Acetylation

The Ac designation represents N-terminal acetylation and forms an important part of the compound’s chemical identity.

Analytical Research

Laboratory analysis may evaluate peptide identity, purity, molecular mass, concentration, stability, and degradation characteristics.

Distinct From Full-Length Thymosin Beta-4

Full-length thymosin beta-4 contains 43 amino acids, whereas TB-500 Fragment is a seven-residue peptide. They should therefore be treated as distinct molecular entities when interpreting research results.

TB-500 Fragment Product Specifications

Product Name: TB-500 Fragment
Sequence: Ac-LKKTETQ
Sequence Length: 7 amino acids
Molecular Formula: C₃₈H₆₈N₁₀O₁₄
Molecular Weight: Approximately 889.0 g/mol
CAS Number: 885340-08-9
Compound Type: Synthetic peptide fragment
Parent Peptide: Thymosin Beta-4
Intended Application: Laboratory and analytical research

Quality & Documentation

Depending on the supplied batch, relevant documentation may include:

  • Peptide identity
  • Sequence information
  • Purity or assay
  • Molecular-weight confirmation
  • Batch or lot number
  • Certificate of Analysis (COA)
  • Analytical testing
  • Stability information
  • Product specifications

The actual product label and batch-specific COA should be treated as the definitive source for the material supplied.

TB-500 Fragment vs Thymosin Beta-4

The terms TB-500, TB-500 Fragment, and Thymosin Beta-4 are sometimes used inconsistently in commercial descriptions.

For scientific accuracy, the molecular identity should be determined by the sequence, molecular weight, CAS number, and analytical documentation,  /product/tb-500-frag/ rather than by the product name alone. Full-length thymosin beta-4 is a 43-amino-acid peptide, whereas the commonly documented TB-500 fragment is the seven-amino-acid Ac-LKKTETQ sequence.

Important Research Information

TB-500 Fragment is presented as a research peptide for laboratory and analytical applications. Research findings involving full-length thymosin beta-4 should not automatically be interpreted as evidence for the TB-500 fragment, because these are different molecular entities.

This product information is intended for scientific, analytical, compound-identification, and legitimate laboratory research purposes. It does not provide dosing, administration, therapeutic, or performance-enhancement instructions.