Description

Telmisartan

Product Overview

Telmisartan is a selective Angiotensin II Receptor Blocker (ARB) widely used in cardiovascular medicine and scientific research. It selectively blocks the angiotensin II type 1 (AT1) receptor, helping researchers investigate blood pressure regulation, vascular biology, renal physiology, and cardiovascular function. In addition to its activity as an ARB, Telmisartan has partial peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist activity, making it valuable in metabolic and endocrine research. Telmisartan is intended for laboratory, scientific research, and approved clinical applications where applicable.

Key Features

  • Selective Angiotensin II Receptor Blocker (ARB)
  • Active ingredient: Telmisartan
  • Partial PPAR-γ agonist activity
  • High-purity pharmaceutical-grade compound
  • Studied in cardiovascular and metabolic research
  • Available in multiple tablet strengths

How It Works

Telmisartan selectively blocks the binding of angiotensin II to the AT1 receptor, preventing vasoconstriction and reducing activation of the renin-angiotensin-aldosterone system (RAAS). Researchers also investigate its partial activation of PPAR-γ, which may influence glucose metabolism, lipid metabolism, and insulin sensitivity. These combined mechanisms make Telmisartan valuable for studies in cardiovascular physiology and metabolic regulation.

Research Applications

Telmisartan is commonly studied in research involving:

  • Renin-angiotensin-aldosterone system (RAAS)
  • Cardiovascular physiology
  • Hypertension research
  • Vascular biology
  • Renal physiology
  • PPAR-γ signaling
  • Metabolic syndrome
  • Insulin sensitivity
  • Endothelial function
  • Clinical pharmacology

Specifications

Property Details
Product Name Telmisartan
Active Ingredient Telmisartan
Drug Class Angiotensin II Receptor Blocker (ARB)
Molecular Formula C33H30N4O2
Molecular Weight 514.62 g/mol
Product Form Oral Tablet
Research Category Cardiovascular & Metabolic Research

Physical Properties

  • Appearance: White to off-white tablet
  • Purity: Pharmaceutical Grade
  • Dosage Form: Oral Tablet
  • Stability: Stable under recommended storage conditions

Storage Instructions

  • Store at 20–25°C in a cool, dry place.
  • Protect from excessive heat, moisture, and direct sunlight.
  • Keep the container tightly closed.
  • Store in the original packaging.
  • Keep out of reach of children.

Packaging Information

Available packaging options may include:

  • 20 mg Tablets
  • 40 mg Tablets
  • 80 mg Tablets
  • Blister Packs
  • Bottle Packaging
  • Bulk pharmaceutical packaging

Quality Assurance

Each production batch undergoes comprehensive quality control testing for:

  • Identity verification
  • Active ingredient assay
  • Purity analysis
  • Dissolution testing
  • Stability assessment
  • Batch-to-batch consistency

Precautions

  • Use only under the supervision of a qualified healthcare professional where applicable.
  • Store according to the recommended conditions.
  • Keep out of reach of children.
  • Handle using appropriate laboratory safety procedures for research applications.
  • Dispose of materials according to applicable regulations.

Shelf Life

Shelf life depends on storage conditions and manufacturer specifications. Refer to the product label or Certificate of Analysis (COA) for expiration details and recommended storage requirements.

Frequently Asked Questions (FAQs)

What is Telmisartan?

Telmisartan is a selective Angiotensin II Receptor Blocker (ARB) that blocks the AT1 receptor and is widely studied in cardiovascular, renal, and metabolic research.

What research areas commonly use Telmisartan?

Researchers commonly investigate Telmisartan in hypertension, cardiovascular physiology, vascular biology, renal function, RAAS signaling, metabolic syndrome, insulin sensitivity, PPAR-γ biology, and clinical pharmacology.

How should Telmisartan be stored?

Store tablets at 20–25°C in a cool, dry place, protected from heat, moisture, and direct sunlight. Keep the container tightly closed.

Is a Certificate of Analysis (COA) available?

Most pharmaceutical manufacturers and research-grade suppliers provide a Certificate of Analysis (COA) with each production batch to verify identity, purity, potency, and overall product quality.