Description

Tadalafil (Cialis)

Product Overview

Tadalafil, commonly known by the brand name Cialis, is a selective phosphodiesterase type 5 (PDE5) inhibitor widely studied for its effects on vascular smooth muscle relaxation and blood flow regulation. It is approved in many countries for specific medical indications and is also investigated in cardiovascular, urological, and vascular physiology research. Tadalafil is distinguished by its relatively long duration of action compared with other PDE5 inhibitors, making it valuable for studies of prolonged PDE5 inhibition and nitric oxide signaling.

Key Features

  • Selective PDE5 inhibitor
  • Active ingredient: Tadalafil
  • High-purity pharmaceutical-grade compound
  • Long-acting pharmacological profile
  • Studied in vascular and urological research
  • Available in multiple tablet strengths

How It Works

Tadalafil selectively inhibits the phosphodiesterase type 5 (PDE5) enzyme, reducing the breakdown of cyclic guanosine monophosphate (cGMP). Increased cGMP levels promote relaxation of vascular smooth muscle and improve blood flow in tissues where nitric oxide signaling is activated. Researchers study this mechanism to better understand endothelial function, vascular physiology, and smooth muscle pharmacology.

Research Applications

Tadalafil is commonly studied in research involving:

  • Vascular biology
  • PDE5 enzyme inhibition
  • Nitric oxide (NO) signaling
  • Endothelial function
  • Cardiovascular physiology
  • Smooth muscle pharmacology
  • Blood flow regulation
  • Pulmonary vascular research
  • Urological research
  • Clinical pharmacology

Specifications

Property Details
Product Name Tadalafil (Cialis)
Active Ingredient Tadalafil
Drug Class Phosphodiesterase Type 5 (PDE5) Inhibitor
Molecular Formula C22H19N3O4
Molecular Weight 389.40 g/mol
Product Form Oral Tablet
Research Category Cardiovascular & Vascular Research

Physical Properties

  • Appearance: Yellow to light yellow film-coated tablet (typical formulation)
  • Purity: Pharmaceutical Grade
  • Dosage Form: Oral Tablet
  • Stability: Stable under recommended storage conditions

Storage Instructions

  • Store at 20–25°C in a cool, dry place.
  • Protect from excessive heat, moisture, and direct sunlight.
  • Keep the container tightly closed.
  • Store in the original packaging.
  • Keep out of reach of children.

Packaging Information

Available packaging options may include:

  • 2.5 mg Tablets
  • 5 mg Tablets
  • 10 mg Tablets
  • 20 mg Tablets
  • Blister Packs
  • Bottle Packaging

Quality Assurance

Each production batch undergoes comprehensive quality control testing for:

  • Identity verification
  • Active ingredient assay
  • Purity analysis
  • Dissolution testing
  • Stability assessment
  • Batch-to-batch consistency

Precautions

  • Use only under the supervision of a qualified healthcare professional.
  • Do not use with nitrate medications due to the risk of severe hypotension.
  • Inform your healthcare provider about any cardiovascular conditions or concurrent medications before use.
  • Store according to the recommended conditions.
  • Keep out of reach of children.

Shelf Life

Shelf life depends on storage conditions and manufacturer specifications. Refer to the product label or Certificate of Analysis (COA) for expiration details and recommended storage requirements.

Frequently Asked Questions (FAQs)

What is Tadalafil?

Tadalafil is a selective PDE5 inhibitor that enhances nitric oxide-mediated vasodilation by increasing cGMP levels, improving blood flow in specific tissues.

What is Tadalafil commonly used for?

Tadalafil is approved in many countries for the treatment of erectile dysfunction (ED), the signs and symptoms of benign prostatic hyperplasia (BPH), and in certain formulations for pulmonary arterial hypertension (PAH). It is also widely studied in cardiovascular and vascular physiology research.

How should Tadalafil be stored?

Store tablets at 20–25°C in a cool, dry place, protected from heat, moisture, and direct sunlight.

Is a Certificate of Analysis (COA) available?

Most pharmaceutical manufacturers and research-grade suppliers provide a Certificate of Analysis (COA) with each production batch to verify identity, purity, potency, and overall product quality.