Description

SS-31 (Elamipretide)

Product Overview

SS-31, also known as Elamipretide, MTP-131, or Bendavia, is a synthetic mitochondria-targeting tetrapeptide developed for laboratory and scientific research. It is designed to selectively bind to cardiolipin, a phospholipid located in the inner mitochondrial membrane, helping researchers investigate mitochondrial structure, energy production, and cellular bioenergetics. SS-31 has been widely studied in mitochondrial dysfunction, cardiovascular research, neurodegenerative diseases, metabolic disorders, and healthy aging. It is intended for laboratory and research use only.

Key Features

  • Synthetic mitochondria-targeting tetrapeptide
  • High-purity research-grade peptide
  • Selectively binds mitochondrial cardiolipin
  • Studied in mitochondrial and cellular energy research
  • Suitable for laboratory and scientific applications
  • Available in multiple research quantities

How It Works

SS-31 selectively accumulates within the inner mitochondrial membrane by binding to cardiolipin. Researchers study its ability to stabilize mitochondrial membrane structure, improve electron transport chain efficiency, reduce oxidative stress, and support ATP production. These mechanisms make SS-31 an important research tool for investigating mitochondrial function and cellular energy metabolism.

Research Applications

SS-31 is commonly studied in research involving:

  • Mitochondrial biology
  • Cellular bioenergetics
  • Oxidative stress
  • Healthy aging research
  • Cardiovascular research
  • Neurodegenerative disease research
  • Skeletal muscle physiology
  • Metabolic disorders
  • Ischemia-reperfusion injury
  • Peptide pharmacology

Specifications

Property Details
Product Name SS-31 (Elamipretide)
Synonyms Elamipretide, MTP-131, Bendavia
CAS Number 736992-21-5
Product Type Synthetic Tetrapeptide
Research Category Mitochondrial & Cellular Energy Research
Appearance White to off-white lyophilized powder

Physical Properties

  • Appearance: White to off-white lyophilized powder
  • Purity: Research Grade
  • Solubility: Soluble in sterile water or suitable laboratory buffers
  • Stability: Stable under recommended storage conditions

Storage Instructions

  • Store refrigerated at 2–8°C.
  • For long-term storage, keep frozen according to the manufacturer’s recommendations.
  • Protect from heat, moisture, and direct sunlight.
  • Keep the vial tightly sealed.
  • Avoid repeated freeze-thaw cycles after reconstitution.

Packaging Information

Available packaging options may include:

  • 5 mg Vial
  • 10 mg Vial
  • Multi-vial research kits
  • Bulk research quantities

Quality Assurance

Each production batch undergoes comprehensive quality control testing for:

  • Identity verification
  • Peptide purity
  • Stability assessment
  • Batch consistency
  • Quality inspection

Precautions

  • Intended for laboratory research purposes only.
  • Not approved for general therapeutic use.
  • Handle using appropriate laboratory safety procedures.
  • Wear suitable personal protective equipment (PPE).
  • Store according to recommended conditions.
  • Keep out of reach of unauthorized personnel.

Shelf Life

Shelf life depends on storage conditions and manufacturer specifications. Refer to the product label or Certificate of Analysis (COA) for expiration details and recommended storage requirements.

Frequently Asked Questions (FAQs)

What is SS-31?

SS-31 (Elamipretide) is a synthetic tetrapeptide designed to target mitochondria by binding to cardiolipin, making it a valuable research tool for studying mitochondrial function, cellular energy production, and oxidative stress.

What research areas commonly use SS-31?

Researchers commonly investigate SS-31 in mitochondrial biology, cardiovascular research, neurodegenerative diseases, metabolic disorders, healthy aging, skeletal muscle physiology, and cellular bioenergetics.

How should SS-31 be stored?

Store refrigerated at 2–8°C before use. For long-term storage, follow the manufacturer’s recommendations and avoid repeated freeze-thaw cycles.

Is a Certificate of Analysis (COA) available?

Most research-grade suppliers provide a Certificate of Analysis (COA) with each production batch to verify identity, purity, and overall product quality.