Description
PE 22-28
Introduction
PE 22-28 is a synthetic heptapeptide derived from spadin and is primarily investigated in laboratory and preclinical research. It has been studied for its interaction with the TREK-1 (TWIK-related potassium channel-1), a potassium channel involved in neuronal signaling. PE 22-28 is considered an investigational compound and is not approved as a therapeutic medicine in many jurisdictions.
Research-grade PE 22-28 is manufactured using controlled peptide synthesis and advanced purification processes designed to support product identity, purity, and batch consistency.
Product Overview
| Specification | Details |
|---|---|
| Product Name | PE 22-28 |
| Category | Synthetic Peptide |
| Peptide Type | Heptapeptide |
| Amino Acid Sequence | Gly-Val-Ser-Trp-Gly-Leu-Arg (GVSWGLR) |
| Form | Lyophilized Powder* |
| Appearance | White to Off-White Powder |
| Purity | Batch Specific |
| Packaging | Sterile Glass Vial |
| Storage | Store Refrigerated at 2°C–8°C |
*Presentation may vary depending on the manufacturer or intended application.
Manufacturing Standards
PE 22-28 is produced using precision peptide synthesis followed by advanced purification techniques designed to support molecular integrity and manufacturing consistency.
Manufacturing processes commonly include:
- Precision peptide synthesis
- Advanced purification methods
- Controlled manufacturing environments
- Batch traceability
- Comprehensive analytical quality testing
Quality Assurance
Each production batch is typically evaluated through quality control procedures that may include:
- Identity verification
- Purity assessment
- Appearance inspection
- Stability evaluation
- Batch consistency testing
- Packaging inspection
These procedures help support reliable manufacturing standards and product integrity.
Physical Characteristics
Typical characteristics include:
- White to off-white lyophilized powder
- Stable peptide formulation under recommended storage conditions
- Sterile vial presentation
- Uniform product appearance
- Clearly labeled packaging
Packaging
Products are generally supplied in protective laboratory packaging that may include:
- Sterile sealed glass vial
- Tamper-evident closure
- Product identification label
- Batch number for traceability
- Protective outer packaging
Storage Recommendations
To help preserve product quality:
- Store refrigerated at 2°C–8°C.
- Protect from direct sunlight.
- Avoid excessive heat and moisture.
- Keep the vial tightly sealed until use.
- Store in the original packaging.
- Do not use if the vial or packaging has been damaged.
Product Features
- Synthetic heptapeptide
- Controlled peptide synthesis
- Advanced purification processes
- Comprehensive analytical quality testing
- Batch traceability
- Sterile laboratory packaging
- Stable formulation under recommended storage conditions

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