Description

VIP (Vasoactive Intestinal Peptide)

Product Overview

Vasoactive Intestinal Peptide (VIP) is a naturally occurring 28-amino acid neuropeptide widely studied for its role in neurotransmission, vasodilation, immune modulation, gastrointestinal physiology, and endocrine signaling. VIP is distributed throughout the central and peripheral nervous systems and is an important regulator of smooth muscle activity, blood flow, and cellular communication. Researchers investigate VIP in neuroscience, immunology, respiratory biology, cardiovascular physiology, and peptide pharmacology. VIP is intended exclusively for laboratory and scientific research purposes.

Key Features

  • Synthetic Vasoactive Intestinal Peptide (VIP)
  • Naturally occurring 28-amino acid neuropeptide
  • High-purity research-grade formulation
  • Studied in neuroscience and immunology
  • Suitable for laboratory and scientific applications
  • Available in multiple research quantities

How It Works

VIP binds primarily to VPAC1 and VPAC2 receptors, members of the G protein-coupled receptor (GPCR) family. Activation of these receptors stimulates intracellular cyclic AMP (cAMP) signaling, influencing smooth muscle relaxation, vasodilation, neurotransmission, immune cell activity, and secretion in various tissues. Researchers study these pathways to better understand cardiovascular regulation, inflammatory responses, and neuroendocrine physiology.

Research Applications

VIP is commonly studied in research involving:

  • Neuroscience
  • Neurotransmitter signaling
  • Immunology
  • Cardiovascular physiology
  • Vasodilation research
  • Gastrointestinal physiology
  • Respiratory biology
  • Endocrine signaling
  • Inflammatory pathways
  • Peptide pharmacology

Specifications

Property Details
Product Name VIP (Vasoactive Intestinal Peptide)
Synonyms Vasoactive Intestinal Polypeptide
Product Type Synthetic Peptide
Amino Acid Length 28 Amino Acids
Molecular Formula C147H237N43O38S
Molecular Weight 3325.80 g/mol
Research Category Neuroscience & Immunology Research
Appearance White to off-white lyophilized powder

Physical Properties

  • Appearance: White to off-white lyophilized powder
  • Purity: Research Grade
  • Solubility: Soluble in sterile water or suitable laboratory buffers
  • Stability: Stable under recommended storage conditions

Storage Instructions

  • Store refrigerated at 2–8°C.
  • For long-term storage, keep frozen according to the manufacturer’s recommendations.
  • Protect from heat, moisture, and direct sunlight.
  • Keep the vial tightly sealed.
  • Avoid repeated freeze-thaw cycles after reconstitution.

Packaging Information

Available packaging options may include:

  • 2 mg Vial
  • 5 mg Vial
  • 10 mg Vial
  • Multi-vial research kits
  • Bulk research quantities

Quality Assurance

Each production batch undergoes comprehensive quality control testing for:

  • Identity verification
  • Peptide purity
  • Stability assessment
  • Batch-to-batch consistency
  • Quality inspection

Precautions

  • Intended for laboratory research purposes only.
  • Handle using appropriate laboratory safety procedures.
  • Wear suitable personal protective equipment (PPE).
  • Store according to recommended conditions.
  • Keep out of reach of unauthorized personnel.

Shelf Life

Shelf life depends on storage conditions and manufacturer specifications. Refer to the product label or Certificate of Analysis (COA) for expiration details and recommended storage requirements.

Frequently Asked Questions (FAQs)

What is VIP?

VIP (Vasoactive Intestinal Peptide) is a naturally occurring 28-amino acid neuropeptide widely studied for its role in neurotransmission, vasodilation, immune regulation, gastrointestinal physiology, and endocrine signaling.

What research areas commonly use VIP?

Researchers commonly investigate VIP in neuroscience, immunology, cardiovascular physiology, respiratory biology, gastrointestinal physiology, inflammatory signaling, neuroendocrine regulation, and peptide pharmacology.

How should VIP be stored?

Store refrigerated at 2–8°C before use. For long-term storage, follow the manufacturer’s recommendations and avoid repeated freeze-thaw cycles after reconstitution.

Is a Certificate of Analysis (COA) available?

Most research-grade manufacturers and suppliers provide a Certificate of Analysis (COA) with each production batch to verify identity, purity, stability, and overall product quality.