Description

Teriparatide

Product Overview

Teriparatide is a synthetic peptide consisting of the first 34 amino acids of human parathyroid hormone (PTH 1–34). It is widely studied in bone biology, calcium homeostasis, skeletal metabolism, and endocrine research. As a biologically active fragment of parathyroid hormone, Teriparatide is investigated for its effects on osteoblast activity, bone remodeling, fracture healing, and mineral metabolism. It is used in approved clinical applications in some settings and is also an important tool in laboratory and scientific research.

Key Features of Teriparatide

  • Synthetic Parathyroid Hormone (PTH 1–34) analogue
  • High-purity research-grade peptide
  • Biologically active fragment of human PTH
  • Studied in bone and endocrine research
  • Suitable for laboratory and scientific applications
  • Available in multiple research quantities

How Teriparatide Works?

Teriparatide binds to parathyroid hormone type 1 (PTH1) receptors located primarily on osteoblasts and bone cells. Researchers investigate its role in regulating bone remodeling, calcium and phosphate metabolism, osteoblast differentiation, and skeletal tissue regeneration. Its receptor-mediated signaling pathways are widely studied to better understand bone formation and endocrine physiology.

Teriparatide Research Applications

Teriparatide is commonly studied in research involving:

  • Bone biology
  • Osteoblast function
  • Bone remodeling
  • Osteoporosis research
  • Fracture healing
  • Calcium homeostasis
  • Skeletal metabolism
  • Endocrine pharmacology
  • Mineral metabolism
  • Regenerative medicine

Specifications

Property Details
Product Name Teriparatide
Synonyms Human Parathyroid Hormone (1–34), PTH (1–34)
Product Type Synthetic Peptide
Molecular Formula C181H291N55O51S2
Molecular Weight 4117.77 g/mol
Research Category Bone & Endocrine Research
Appearance White to off-white lyophilized powder

Physical Properties

  • Appearance: White to off-white lyophilized powder
  • Purity: Research Grade
  • Solubility: Soluble in sterile water or suitable laboratory buffers
  • Stability: Stable under recommended storage conditions

Storage Instructions

  • Store refrigerated at 2–8°C.
  • For long-term storage, keep frozen according to the manufacturer’s recommendations.
  • Protect from heat, moisture, and direct sunlight.
  • Keep the vial tightly sealed.
  • Avoid repeated freeze-thaw cycles after reconstitution.

Packaging Information

Available packaging options may include:

  • 5 mg Vial
  • 10 mg Vial
  • Multi-vial research kits
  • Bulk research quantities

Quality Assurance

Each production batch undergoes comprehensive quality control testing for:

  • Identity verification
  • Peptide purity
  • Stability assessment
  • Batch consistency
  • Quality inspection

Precautions

  • Intended for laboratory research purposes or approved clinical use where applicable.
  • Handle using appropriate laboratory safety procedures.
  • Wear suitable personal protective equipment (PPE).
  • Store according to recommended conditions.
  • Keep out of reach of unauthorized personnel.

Shelf Life

Shelf life depends on storage conditions and manufacturer specifications. Refer to the product label or Certificate of Analysis (COA) for expiration details and recommended storage requirements.

Frequently Asked Questions (FAQs)

What is Teriparatide?

Teriparatide is a synthetic peptide corresponding to the first 34 amino acids of human parathyroid hormone (PTH), widely studied for its role in bone formation, skeletal metabolism, and calcium regulation.

What research areas commonly use Teriparatide?

Researchers commonly investigate Teriparatide in bone biology, osteoporosis, fracture healing, osteoblast activity, calcium homeostasis, skeletal metabolism, regenerative medicine, and endocrine pharmacology.

How should Teriparatide be stored?

Store refrigerated at 2–8°C before use. For long-term storage, follow the manufacturer’s recommendations and avoid repeated freeze-thaw cycles after reconstitution.

Is a Certificate of Analysis (COA) available?

Most research-grade manufacturers and suppliers provide a Certificate of Analysis (COA) with each production batch to verify identity, purity, stability, and overall product quality.